Keto Diet Specialist: What The Keto Diet Is Really Doing To Your Body! Can It Cure 43% Of Mental Illnesses? The Truth About The Keto Diet!

Jan 16, 2025
Overview

Dr. Georgia Ede, a Harvard-trained psychiatrist, discusses how nutrition and metabolic health profoundly impact mental well-being. She explains how dietary changes, like the ketogenic diet, can address root causes of mental illness by improving brain metabolism and reducing inflammation, often more effectively than medication.

At a Glance
24 Insights
1h 48m Duration
13 Topics
6 Concepts

Deep Dive Analysis

Introduction to Metabolic Psychiatry and Ketogenic Diet

Dr. Ede's Personal Journey and Eureka Moment

Fundamental Principles of a Healthy Diet: Nourish, Protect, Energize

Understanding the Ketogenic Diet and its Brain Impact

Ketogenic Diet's Impact on Refractory Mental Illnesses

Sustainability Challenges and 'Keto-Flu'

Misconceptions and Definition of Ketosis

Food and Neurodivergent Disorders like ADHD

Ketogenic Diet Benefits for Food Addiction and Case Studies

Discussion on the Carnivore Diet and Fiber

Ketogenic Diet for Weight Loss

Psychological Aspects of Dietary Change

Ketogenic Diet's Role in Reducing Anxiety

Metabolic Psychiatry

A very new and exciting field that explores how food and brain metabolism affect mental health. It focuses on identifying and addressing root causes of mental health conditions such as inflammation, oxidative stress, and insulin resistance, moving beyond traditional explanations like mysterious chemical imbalances.

Ketogenic Diet

A dietary approach, originally created over 100 years ago to stabilize brain chemistry in children with severe seizures. Its definition is any diet that lowers insulin levels to the 'fat burning point,' causing the liver to produce ketones for energy, thus fundamentally changing the brain's operating system in healthy ways.

Insulin Resistance

A condition where cells become less responsive to insulin, leading to chronically high insulin levels. It is identified as a primary driver of mental health conditions, inflammation, and oxidative stress, affecting a significant portion of the population.

Ketosis

A metabolic state where glucose and insulin levels are low enough, and the stored starch in the liver is largely depleted, causing the body to burn fat and produce ketones (beta-hydroxybutyrate) for energy. A blood ketone level of 0.5 millimole or higher is generally considered to indicate a state of ketosis.

Keto Flu

A common experience of uncomfortable symptoms during the transition from a carbohydrate-burning metabolism to a fat-burning metabolism. These symptoms can often be prevented or mitigated through electrolyte supplementation and a gradual transition onto the ketogenic diet.

Nourish, Protect, Energize

Three fundamental principles for a brain-healthy diet. 'Nourish' means consuming foods that provide all essential nutrients (which requires some animal foods). 'Protect' involves excluding damaging ingredients like refined carbohydrates and vegetable oils. 'Energize' focuses on maintaining healthy glucose and insulin levels for clean, efficient brain energy.

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What is metabolic psychiatry?

Metabolic psychiatry is a very new and exciting field that explores how food and brain metabolism affect mental health, focusing on root causes like inflammation, oxidative stress, and insulin resistance, rather than just mysterious chemical imbalances.

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Why is the ketogenic diet central to Dr. Ede's work?

The ketogenic diet fundamentally changes the brain's operating system by switching from a high-carbohydrate, high-insulin state to a low-insulin state, allowing brain cells to work better and heal by reducing inflammation, oxidative stress, and insulin resistance.

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What are the fundamental principles of a healthy diet?

A brain-healthy diet must nourish cells with all essential nutrients (requiring some animal foods), protect the brain from damaging ingredients like refined carbohydrates and vegetable oils, and energize cells by maintaining healthy glucose and insulin levels.

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What is the ketogenic diet?

The ketogenic diet is any way of eating designed to lower insulin levels sufficiently to turn on fat burning and generate ketones in the blood, originally developed over 100 years ago to stabilize brain chemistry in children with severe seizures.

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How does the ketogenic diet impact the brain?

The ketogenic diet acts as a multi-purpose tool for brain health by reducing inflammation, oxidative stress, and insulin resistance, while also improving the balance of brain chemicals and enabling reliable energy production.

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Why is the ketogenic diet difficult to sustain for some people?

While it stabilizes appetite hormones and can make healthy eating easier, it's challenging to follow in a high-carbohydrate world due to environmental and social temptations, habits, and sugar addiction.

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Can diet modifications alleviate ADHD symptoms?

Studies from the 1980s-2000s in Europe showed 62-82% response rates and even 70% cure rates in children with ADHD on 'few foods' diets, suggesting food can be a significant factor, though major health organizations currently deem evidence insufficient for widespread recommendation.

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Does the carnivore diet provide all essential nutrients?

Theoretically, a diet consisting solely of meat, seafood, and poultry can provide all essential nutrients, unlike any single plant food.

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Why does the ketogenic diet help with weight loss?

The ketogenic diet helps with weight loss by lowering insulin levels, as the body cannot burn fat effectively when insulin levels are too high. Ketones on a meter indicate that the body is in fat-burning mode.

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What role does the ketogenic diet play in reducing anxiety?

Most people experience significant reductions in anxiety within days to weeks of starting a ketogenic diet, likely due to the stabilization of glucose and insulin levels, which in turn stabilizes stress hormones.

1. Prioritize Dietary Subtraction

Focus on removing harmful ingredients from your diet, rather than adding ‘superfoods’ or supplements, as subtraction is often the most powerful first step for brain health.

2. Address Root Causes Mental Illness

Focus on addressing inflammation, oxidative stress, and insulin resistance as the primary root causes of mental health conditions, rather than solely relying on medications.

3. Ketogenic Diet for Brain Healing

Adopt a ketogenic diet to fundamentally change the brain’s operating system, enabling brain cells to work better and promoting long-term healing and recovery.

4. Optimize Glucose and Insulin Levels

Energize your brain by maintaining healthy glucose and insulin levels, as this allows the brain to generate energy efficiently and reliably, improving overall function.

5. Stabilize Appetite with Ketosis

Use a ketogenic diet to stabilize appetite hormones and avoid glucose spikes and crashes, which leads to sustained energy and reduces constant food cravings, making healthy eating easier.

6. Ketogenic Diet for Anxiety Reduction

Consider adopting a ketogenic diet for significant anxiety reduction, as many experience improvements within 3 days to 3 weeks due to its effect on brain chemistry.

7. Ketosis for Emotional Buffer

Use ketosis to create an emotional buffer, allowing you to gain perspective and respond more effectively to difficult situations rather than reacting reflexively, as it stabilizes mood and thought processes.

8. Include Animal Foods for Nutrients

Ensure your diet includes some animal foods (meat, seafood, poultry) to safely deliver all essential nutrients, as plant-based diets alone cannot meet this requirement without supplementation.

9. Eliminate Inflammatory Foods

Protect your brain by subtracting foods that cause inflammation and oxidative stress, such as refined carbohydrates and vegetable oils, which are common in the standard Western diet.

10. Assess Metabolic Health for Carbs

Determine your personal carbohydrate tolerance by assessing your metabolic health and insulin resistance, as this guides how much carbohydrate you can safely consume for optimal brain energy.

11. Ease Keto Transition with Electrolytes

Prevent or minimize ‘keto flu’ symptoms by supplementing electrolytes to maintain salt balance and by gradually transitioning onto the ketogenic diet over a week or two, rather than abruptly.

12. Monitor Ketone Levels for Fat

Use a blood ketone meter to confirm ketosis (0.5 millimole or higher beta-hydroxybutyrate), indicating that glucose and insulin levels are low enough and liver glycogen is depleted, allowing fat burning.

13. Intermittent Ketosis for Cellular Healing

Incorporate periods of ketosis, even intermittently, into your routine to activate essential healing, recycling, and maintenance pathways in your cells, preventing breakdown and promoting well-being.

14. Avoid Ultra-Processed Carbohydrates

Recognize that ultra-processed, refined carbohydrates are designed to bypass satiety signals, leading to overeating; stepping away from them can restore hormonal control and provide freedom from cravings.

15. Explore Elimination Diets for ADHD

Consider a ‘few foods’ or oligoantigenic diet for children with ADHD, as studies show significant improvement and even ‘cure’ rates within weeks by identifying and removing problematic foods.

16. Supervise Ketogenic Diet with Meds

If on psychiatric or other medications, implement a ketogenic diet under careful medical and psychiatric supervision, as brain chemistry changes can affect medication efficacy and require monitoring.

17. Address Psychology of Food Relationship

Recognize and address the complex psychological, emotional, and social aspects of your relationship with food, as this understanding is crucial for successful and sustainable dietary changes.

18. Adopt Team Approach for Diet

For significant dietary changes, especially for mental health, consider a team approach involving a keto dietitian, a prescribing professional (if on medication), and a coach or therapist for comprehensive support and motivation.

19. Use CGM for Glucose Monitoring

Utilize a continuous glucose monitor (CGM) to observe how your glucose levels respond to food, exercise, and lifestyle choices, providing valuable data for optimizing metabolic health.

20. Re-evaluate Fiber’s Role in Diet

Reconsider the traditional emphasis on fiber; it’s not an essential nutrient, and its benefits (like glucose regulation or gut health) can often be achieved more effectively through other dietary adjustments or metabolic states like ketosis.

21. Identify Food Intolerances

Recognize that environmental toxins can lead to food intolerances; use trial and error, guided by lists of common culprits, to identify and remove foods that your body can no longer safely tolerate.

22. Adapt Lifestyle to ADHD Strengths

For ADHD management, adapt your lifestyle to leverage your strengths and avoid struggling against weaknesses, as this can be a powerful intervention for improving function and well-being.

23. Consider Carnivore Diet for Mood

For severe, treatment-resistant depression and anxiety, consider exploring a carnivore diet (fatty meat only) as a radical intervention, as it has shown rapid and profound symptom resolution for some individuals.

24. Adopt Nutritional Pro-Choice Philosophy

Adopt a ’nutritionally pro-choice’ mindset, focusing on optimizing a diet that aligns with your personal preferences and comfort, as long-term adherence is crucial for sustained brain health benefits.

Most people will experience tremendous reductions in anxiety within three days to three weeks of starting a ketogenic diet.

Dr. Georgia Ede

The real drivers, the primary drivers of mental health conditions are inflammation of the brain, something called oxidative stress, which is why we're always told to eat more antioxidants, and insulin resistance or pre-diabetes, which is now affects more than 90% of Americans.

Dr. Georgia Ede

The real power in dietary change is not adding special things to the diet. But it's actually subtracting the things that are harming the brain and working against your best efforts.

Dr. Georgia Ede

The definition of a ketogenic diet is any diet that lowers insulin levels to the fat burning point.

Dr. Georgia Ede

If you cannot burn fat, if your insulin levels are too high.

Dr. Georgia Ede

Most of what we believe about nutrition is untested theories, wild guesses, and wishful thinking.

Dr. Georgia Ede

Hope is on the menu.

Dr. Georgia Ede

Transitioning to a Ketogenic Diet

Dr. Georgia Ede
  1. Supplement electrolytes to keep your salt balance even as you're transitioning.
  2. Transition slowly onto the ketogenic diet over a week or two, rather than all at once, using a moderate carbohydrate plan.
  3. Aim for good, consistent, daily ketosis for at least six weeks straight, tracking ketone levels with a blood ketone meter (0.5 millimole or higher).
  4. Tweak your dietary plan based on ketone readings to maintain ketosis.
More than 90%
Percentage of Americans affected by insulin resistance or pre-diabetes A primary driver of mental health conditions
10 years
Duration of Dr. Ede's conventional psychiatric practice before exploring nutrition Before realizing most patients weren't improving significantly
1921
Year the ketogenic diet was originally created To stabilize brain chemistry in children with severe seizures
More than 50%
Seizure response rate for children and adults on a ketogenic diet In studies for severe seizures
10% to 20%
Percentage of children and adults completely free of seizures on a ketogenic diet In studies for severe seizures
31
Number of patients in Dr. Denault's study on ketogenic diet for refractory mental illness Adults with bipolar disorder, major depression, or schizophrenia
10 years
Average duration of illness for patients in Dr. Denault's study Some for as long as 30 years
5
Average number of psychiatric medications taken by patients in Dr. Denault's study Upon entering the hospital
43%
Percentage of patients in Dr. Denault's study who achieved clinical remission From their primary psychiatric illness
64%
Percentage of patients in Dr. Denault's study who left on less psychiatric medication Due to improvements
More than 2 weeks
Minimum duration on ketogenic diet to start seeing benefit As observed in Dr. Denault's study
Below 750 grams per day
Calorie restriction threshold for many people to enter ketosis Another version of a fasting-mimicking diet
0.5 millimole or higher
Blood ketone level for being 'in ketosis' Measured by a blood ketone meter
62% to 82%
Response rate to 'few foods' diets for children with ADHD Observed in studies from the 1980s-2000s in Europe
70%
Cure rate for children with severe ADHD on 'few foods' diets Within weeks in some studies
Twice as likely
Increased likelihood of ADHD for children with obesity Obesity is a marker for insulin resistance
Twice as likely
Increased likelihood of ADHD for adults with type 2 diabetes Type 2 diabetes is severe end-stage insulin resistance
$45 or $50
Cost of a single two-week glucose sensor (US over-the-counter) Recommended for monitoring glucose levels