Andrew Huberman: My Exact Routine To Optimize Brain & Body, I Do All Of These Every Day!

Sep 3, 2026 Transcript ↗
Overview

Stanford Neuroscientist Andrew Huberman, Ph.D., shares 10 actionable protocols for optimizing mental and physical health. He details strategies for improving sleep, managing stress, enhancing focus, and leveraging light and nutrition, along with insights on personal growth and the role of faith.

At a Glance
14 Insights
2h 16m Duration
19 Topics
8 Concepts

Deep Dive Analysis

Introduction to Protocols for Mental and Physical Health

The Healthy Cortisol Curve and Its Importance

Hydration and Morning Cortisol Boost

The Power of Morning Sunlight and Daylight Exposure

Offsetting Night Shifts and Screen Time Effects

Optimal Exercise Routine for All-Round Fitness

Building Willpower and Tenacity Through Challenge

Understanding the Autonomic Nervous System and Stress

Real-Time Stress Reduction Techniques

The Eye Movement Trick to Fall Back Asleep

The Truth About Peptides and Their Application

Psychedelics, Reality, and the Concept of God

The Role of Faith and Prayer in Life

Creating an Ideal Sleep Environment

Importance of Daily Effortful Mental Work and Learning

Glymphatic Drainage and Brain Health

Supplement Recommendations for Health and Focus

Benefits of Post-Meal Walking and Movement

Maintaining Metabolism with Age

Cortisol Awakening Response

The natural and beneficial surge of cortisol in the first hour of waking, which is crucial for establishing daytime alertness, mood, and focus, and for ensuring lower cortisol levels at night for quality sleep.

Anterior Mid-Cingulate Cortex

A brain region responsible for tenacity and willpower, which can be strengthened through engaging in challenging activities, making individuals more resilient to future difficulties.

Autonomic Nervous System

The involuntary control system comprising the sympathetic (fight-or-flight, alertness) and parasympathetic (rest-and-digest, calming) branches, which regulate the body's arousal states.

Physiological Sigh

A specific breathing pattern involving two short inhales followed by a long exhale, which rapidly reduces stress by maximally inflating lung sacs and efficiently expelling carbon dioxide.

Respiratory Sinus Arrhythmia

The natural variation in heart rate that occurs with breathing, where heart rate slows during exhalation, reflecting parasympathetic nervous system activity and indicating higher heart rate variability (HRV).

Glymphatic Clearance

A brain waste removal system that becomes highly active during sleep, flushing out metabolic byproducts and contributing to cognitive function, feeling rested, and reducing under-eye puffiness.

High Complete Protein to Calorie Ratio

A dietary principle focusing on consuming protein sources that provide all essential amino acids with a relatively low caloric load, such as lean meats, fish, and eggs, to optimize nutrient intake.

Top-Down Inhibition

The cognitive ability to suppress impulses and control automatic responses, primarily governed by the prefrontal cortex, which is vital for thoughtful decision-making and is impaired by fatigue or stress.

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Why is high cortisol in the morning a good thing?

High morning cortisol, known as the cortisol awakening response, is essential for elevated mood, focus, attention, and learning, and it helps establish low cortisol levels needed for good sleep at night.

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How can I quickly reduce stress in the moment?

Performing physiological sighs (a double inhale followed by a long exhale) can rapidly slow your heart rate and offload carbon dioxide, effectively calming your nervous system.

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What is the best way to fall back asleep if I wake up in the middle of the night?

Close your eyes and slowly move them in specific patterns (side-to-side, up-and-down, circles, pointing towards nostrils) combined with long exhales, which helps shut down proprioceptive circuits and facilitates sleep.

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How does viewing morning sunlight benefit my health?

Viewing morning sunlight or bright daylight activates specific cells in your eyes that signal your master circadian clock, triggering cortisol release, improving mood, metabolism, immune function, and buffering stress later in the day.

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Does deliberate cold exposure raise cortisol?

No, deliberate cold exposure results in trivial increases in cortisol, but significantly increases adrenaline, norepinephrine, and dopamine, which are beneficial for alertness and focus.

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How can I improve my willpower and tenacity?

Engaging in voluntary difficult things, whether physical or cognitive, strengthens the anterior mid-cingulate cortex, a brain area associated with tenacity, making you more willing to tackle future challenges.

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What is the ideal exercise routine for overall fitness?

An optimal routine involves alternating three days of resistance training (emphasizing compound movements near failure) with three days of varied cardio (long-slow, moderate, and HIIT), taking one rest day.

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How can I improve my focus and cognitive capacity?

Removing your phone from the room during effortful mental work significantly increases focus and cognitive flexibility, as the mere presence of the phone can create a subconscious distraction.

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What is the best way to learn and retain knowledge?

Engage in effortful learning where you make genuine attempts and experience a 15% error rate, followed by self-testing (e.g., using an AI tool or mental recall) to reinforce what you've learned.

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How does diet impact stress and sleep?

Consuming starches can lower cortisol levels, which is beneficial for sleep, as low cortisol is desired at night. However, excessive fiber can sometimes increase inflammatory markers for some individuals.

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Do supplements help with health and focus?

While behavioral tools are foundational, certain supplements like magnesium threonate/bisglycinate (for sleep), EPA omega-3 (for brain/cardio health), Vitamin D (5,000-10,000 IU), and Alpha GPC (for focus) can provide additional benefits when used judiciously.

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How can I reduce blood sugar spikes after eating?

Taking a 5-10 minute walk after meals helps buffer blood glucose peaks through low-level muscle contractions, reducing energy crashes and supporting metabolic health.

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Does metabolism decline with age?

The decline in metabolism often associated with aging is not inherent but is largely linked to a reduction in muscle mass and spontaneous movement, suggesting that maintaining activity can preserve metabolic rate.

1. Get Afternoon/Evening Daylight Exposure

View daylight in the late afternoon or last third of your day (without sunglasses) to buffer your eyes against the negative effects of artificial light at night, reducing its impact on melatonin and blood glucose.

2. Ensure Dark Nights for Health

Keep your sleeping environment as dark as possible and dim artificial lights in the evening, as bright nights are linked to shorter lifespans and metabolic unhealthiness.

3. Remove Phone from Workspace

To enhance focus and cognitive flexibility during effortful work, keep your phone out of the room entirely, as its mere presence in the room can diminish cognitive capacity.

4. Engage in Daily Effortful Learning

Dedicate 90 minutes to two hours daily to mentally challenging work or learning, embracing friction and errors, as this stimulates neuroplasticity and improves focus and cognitive capacity.

5. Self-Test for Knowledge Retention

Regularly self-test on learned material to reinforce knowledge and improve long-term retention, rather than just rereading or highlighting content.

6. Prioritize High Protein-to-Calorie Foods

Focus on consuming proteins with a high complete protein to calorie ratio (e.g., eggs, lean meat, fish) to meet protein needs without excessive calorie intake.

7. Include Low-Sugar Fermented Foods

Incorporate low-sugar fermented foods like sauerkraut or kimchi into your diet to lower inflammatory markers and improve gut health.

8. Use Olive Oil for Fats

Opt for olive oil as a primary fat source due to strong supporting data and its relatively inexpensive nature, avoiding debates around seed oils.

9. Consume Starches for Cortisol Buffer

Include starches in your diet, especially in the final meal of the day, as they increase glucose, which helps lower cortisol and can improve sleep.

10. Walk After Meals for Glucose Control

Take a 5-10 minute walk after meals to buffer blood glucose peaks, reduce energy crashes, and support metabolic health through low-level muscle contractions.

11. Maintain Muscle Mass for Metabolism

Prioritize resistance training and maintain muscle mass throughout life, as declining metabolism with age is largely linked to reduced muscle mass and spontaneous movement.

12. Embrace Faith and Prayer

Consider embracing faith and prayer as a practice to relieve the pressure of controlling everything, find peace, and potentially experience unexpected positive outcomes in life.

13. Short Daytime Meditation for Brain Clearance

Engage in short meditations (e.g., 10 breaths) during the day to increase glymphatic clearance, potentially allowing for slightly less sleep without compromising brain health.

14. Consider Specific Supplements

If needed, explore magnesium threonate/bisglycinate for sleep, EPA omega-3 (prescription Lovasa recommended), 5,000-10,000 IU Vitamin D, and Alpha GPC (with garlic capsule) for focus, after consulting a doctor.

High cortisol in the early part of your day is what provides for elevated mood, focus, attention, your ability to learn. It's also what establishes low cortisol in the afternoon and at night, which is a requirement for falling and staying asleep.

Andrew Huberman

When you do something that you don't want to do, that you don't reflexively do, your anterior mid-cingulate cortex gets bigger and more willing to engage in challenging things going forward.

Andrew Huberman

In the first 20 to 30 seconds [of a stressful circumstance], you are brain damaged.

Andrew Huberman

The thirst proves the existence of water.

Arthur Brooks (quoted by Andrew Huberman)

You find [your calling] while working your butt off doing something else. That's how.

James Hollis (quoted by Andrew Huberman)

Your understanding of the world is an abstraction that occurs inside your skull on the basis of photons that come in through your eyes, sound waves that hit your ears, mechanical forces that hit your skin, and chemicals that go in your nostrils and in your mouth.

Andrew Huberman

Faith is the infrared goggles of human understanding about why we're here.

Andrew Huberman

Morning Cortisol Optimization Protocol

Andrew Huberman
  1. Consume 16-32 ounces of clean water upon waking.
  2. View sunlight or bright daylight (10,000 lux artificial light if needed) for 10-15 minutes (longer on overcast days) within the first hour of waking.
  3. Perform cardiovascular or resistance training within the first 3-4 hours of the day.

Real-Time Stress Reduction Protocol

Andrew Huberman
  1. Perform a physiological sigh: a double inhale through the nose, followed by a long, complete exhale through the mouth.
  2. Repeat 1-3 times as needed to calm the nervous system.

Falling Back Asleep Eye Movement Protocol

Andrew Huberman
  1. Close your eyes.
  2. Slowly move your eyes to one side underneath your eyelids, then to the other side.
  3. Move your eyes up, then down.
  4. Move your eyes counterclockwise in a circular motion, then clockwise in a circular motion.
  5. Point your eyes towards your nostrils (without crossing them).
  6. Perform a long exhale.
  7. Repeat 2-3 times.

Daily Personal Development Practice

James Hollis (cited by Andrew Huberman)
  1. Shut Up: Practice gratitude and acknowledge suffering in others.
  2. Suit Up: Prepare for the day by taking care of health and getting organized.
  3. Show Up: Fulfill outward roles and responsibilities for the world (e.g., father, mother, teacher, mechanic).
  4. Exit Stimulus-Response Mode: Once a day, engage in an activity like meditation, drawing, or listening to music without trying to accomplish anything, allowing the unconscious mind to provide insights into your deepest desires.
16 to 32 ounces
Water intake upon waking Of clean water, to boost morning cortisol and mental sharpness.
Approximately 80 ounces
Daily water intake Recommended throughout the day.
10,000 lux
Lux for artificial light For artificial light exposure, if natural sunlight is unavailable in the morning.
About 8 centimeters
Red light penetration Depth red light can penetrate into the body.
Over 40
Vision improvement age Age group that can experience vision improvements from viewing long wavelength light.
First three hours of the day
Vision improvement timing Window for people over 40 to view long wavelength light for vision benefits.
First 20 to 30 seconds
Stress response time Duration during which the prefrontal cortex is greatly suppressed in stressful circumstances.
1,000-fold or more
GLP-1 increase with drugs Levels of glucagon-like peptide increased by GLP-1 weight loss drugs.
Approximately one-third of body weight
GLP-1 weight loss Observed weight loss in about a year with retitrutide in phase three trials.
Every third night
Pinealon dosage frequency Andrew Huberman's personal experimental frequency for massive REM sleep.
Around 15% on average
Optimal learning error rate Computational modeling suggests this error rate is ideal for stimulating neuroplasticity during learning.
At least 1 gram per day
EPA Omega-3 dosage Recommended for brain and cardiovascular health, and reduced inflammation.
5,000 to 10,000 IU per day
Vitamin D dosage Suggested range for benefits beyond conventional RDA, including hormone health.
600 milligrams or 900 milligrams
Alpha GPC dosage For increasing choline and acetylcholine to enhance focus and REM sleep.
600 milligrams
Garlic capsule for TMAO To mitigate increased cardiovascular risk from Alpha GPC by reducing TMAO.
200 to 400 milligrams per day
Caffeine for dementia offset Correlative data suggest this amount can offset dementia in meaningful ways.
5 to 10 grams per day
Creatine dosage For maintaining/building strength and cognitive enhancement when sleep-deprived or stressed.
7,000 to 8,000 steps per day
Daily steps goal Recommended for overall health, with walking after meals being particularly beneficial.
About 1% of total musculature
Soleus muscle percentage Despite its small size, it has outsized glucose utilization.
Up to 1,800 calories a day
Non-exercise thermogenesis calorie burn Observed in extreme movers; some people burn 1,000 calories a day through spontaneous movement.
Above 1,000 parts per million
CO2 level for cognitive decline Studies suggest cognitive performance starts to decline at this level of CO2.