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1. Prioritize Muscle-Building Exercise
Engage in muscle-building activities, as they are more effective than aerobic exercise for improving insulin sensitivity and consuming glucose, which also predicts longevity.
2. Control Carbohydrate Intake
Focus on whole fruits and vegetables, and avoid processed carbohydrates from bags, boxes, and barcodes, as carbohydrates are not essential and significantly spike insulin.
3. Prioritize Protein Consumption
Emphasize animal-sourced protein, which provides all essential amino acids and, when combined with fat, promotes satiety and greater muscle growth.
4. Don’t Fear Dietary Fat
Include healthy fats with protein in your diet, as this combination is highly satiating, aids digestion, and is crucial for overall health and energy.
5. Practice Frequent Fasting
After adopting better eating habits (controlling carbs, prioritizing protein/fat), implement structured fasting periods to lower insulin, promote fat burning, and enhance cellular autophagy.
6. Increase Fat Intake on Ketogenic Diet
If following a ketogenic diet and aiming to preserve muscle mass, ensure sufficient fat intake, as muscle is metabolically expensive and needs adequate fuel to prevent breakdown.
7. Boost Salt and Hydration on Low-Carb Diets
When insulin levels drop due to carbohydrate restriction, the body eliminates more salt and water, making increased hydration and salt intake crucial to prevent dehydration and maintain performance.
8. Choose Insulin-Neutral Sweeteners
Opt for sweeteners like aspartame, erythritol, monk fruit extract, stevia, and allulose, as they have no impact on insulin levels, unlike some sugar alcohols or sucralose.
9. Avoid Sucralose
Steer clear of sucralose (found in many ‘zero’ drinks) because it can cross the blood-brain barrier, and its long-term effects there are unknown.
10. Do Not Restrict Dietary Salt
Contrary to popular belief, restricting salt has a negligible effect on blood pressure and can even cause insulin resistance; focus instead on reducing refined starches and sugars.
11. Measure Fasting Insulin Levels
Get your fasting insulin levels checked, as many people with insulin resistance have normal blood glucose but elevated insulin (above 10 microunits/mL in US or 40 picomoles/L in UK units).
12. Manage Stress Effectively
Actively work to reduce stress, as elevated stress hormones (cortisol, adrenaline) quickly cause insulin resistance by pushing blood glucose levels up.
13. Prioritize Quality Sleep
Ensure adequate sleep, as sleep deprivation is a potent way to increase cortisol and thus contribute to insulin resistance.
14. Moderate Caffeine Intake
Be mindful of caffeine consumption, as excessive amounts can strongly increase epinephrine, contributing to stress-induced insulin resistance.
15. Reduce Inflammation
Address sources of inflammation in the body, as inflammation directly increases insulin resistance.
16. Be Mindful of Air Quality
Recognize that inhaled particulates, such as diesel exhaust, can contribute to increased fat mass, enlarged fat cells, and insulin resistance.
17. Avoid Microplastics and Endocrine Disruptors
Limit exposure to microplastics and chemicals like BPA or DES found in plastics, soaps, and detergents, as they can directly promote fat cell growth and impact metabolic health.
18. Limit Sugar During Pregnancy
Pregnant women should be especially mindful of sugar intake, as excessive sugar can compound physiological insulin resistance into gestational diabetes, negatively impacting both mother and baby.
19. Avoid ‘Eat Less, Exercise More’ for Weight Loss
This traditional advice often leads to increased hunger and metabolic damage, making long-term weight loss unsustainable; instead, focus on lowering insulin to naturally reduce hunger.
20. Be Cautious with GLP-1 Weight Loss Drugs
Understand that GLP-1 receptor agonists can lead to significant loss of lean mass (muscle and bone), and may increase the risk of suicidal thoughts and depression.
21. Use GLP-1 Drugs Responsibly
If using GLP-1 drugs, combine them with proper education, prioritize protein and fat, lift weights to preserve lean mass, and aim for the lowest effective dose with a plan to eventually taper off.
22. Avoid Liposuction for Metabolic Health
Liposuction removes fat cells but does not improve metabolic health; it can lead to remaining fat cells growing larger and fat being stored in less healthy areas like the abdomen, worsening metabolic outcomes if lifestyle habits are not changed.
23. Avoid Vaping
Vaping is likely worse than smoking in terms of inflammatory effects, damage to the airway, and contribution to insulin resistance.
24. Consume Animal-Sourced Omega-3s
Ensure adequate intake of essential omega-3 fats, particularly EPA and DHA, which are primarily found in animal-sourced foods and are crucial for brain health.
25. Vegans Must Supplement Essential Nutrients
Vegans should be educated on potential nutrient deficiencies (e.g., essential omega-3s) and supplement accordingly to support brain health and overall well-being.
26. Monitor Triglyceride Levels
Pay attention to triglyceride levels, as they are a more predictive marker for heart attack risk than cholesterol levels.