BITESIZE | Do This Every Morning to Optimise Your Health, Boost Your Mood and Improve Your Sleep | Professor Russell Foster #488

Oct 24, 2024 Episode Page ↗
Overview

Russell Foster, Professor of Circadian Neuroscience, discusses how light acts as a powerful "drug" to optimize health, boost mood, and improve sleep by setting our internal clock. He emphasizes the critical role of morning light and the impact of daily light exposure on our circadian rhythm.

At a Glance
5 Insights
16m 57s Duration
12 Topics
5 Concepts

Deep Dive Analysis

Light as a Powerful Biological Regulator

The Suprachiasmatic Nuclei: Our Master Internal Clock

How Light Entrains the Body Clock

Morning Light's Crucial Role in Daily Nudging

Addressing Winter Morning Light Challenges

Light Therapy for Seasonal and Non-Seasonal Depression

Comparing Light's Efficacy to Antidepressant Medication

Understanding Lux Levels in Different Environments

Daytime Light Exposure Mitigates Nighttime Effects

Light's Direct Alerting Effect vs. Clock Shifting

Synergistic Alerting Effects of Screens and Content

Importance of Winding Down Before Sleep

Internal Clock / Suprachiasmatic Nuclei (SCN)

This is a master clock located within the brain, specifically a small paired structure of about 50,000 cells situated above where the optic nerves fuse. Each cell in the SCN is capable of generating its own endogenous 24-hour rhythm.

Molecular Feedback Loop (of SCN)

The mechanism by which the SCN generates its rhythm involves clock genes being activated to produce proteins. These proteins then form a complex, which enters the cell nucleus to turn off their own genes, after which the protein complex is degraded, allowing the cycle to restart, creating a biological oscillation of approximately 24 hours.

Entrainment

This is the process by which the internal body clock, which naturally runs slightly longer or shorter than 24 hours, is aligned or 'set' to the actual 24-hour external day. Light is identified as the most important environmental cue for this daily alignment.

Chronotype

This refers to an individual's natural predisposition to be a 'morning person' or an 'evening person' based on their preferred sleep-wake times. The episode notes that individuals with a later chronotype tend to receive more evening light and less morning light, which further delays their body clock.

Lux

Lux is a unit of measurement for light intensity. Outdoor light levels can range from 10,000 lux shortly after dawn to 100,000 lux at noon, while indoor light levels are significantly lower, often only reaching hundreds or even tens of lux.

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What is the 'internal clock' in our brain?

The internal clock is a master clock called the suprachiasmatic nuclei (SCN), a small paired structure of about 50,000 cells located above where the optic nerves fuse, with each cell capable of generating an endogenous 24-hour rhythm.

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Why is morning light so important for our body clock?

Morning light is crucial because about 90% of people have a body clock slightly longer than 24 hours, and morning light provides the necessary daily 'advance' or 'nudge' to align the internal clock with the external 24-hour day, helping us wake up earlier.

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Can artificial light, like SAD lamps, be useful for regulating the body clock?

Yes, artificial light from light boxes producing 2,000 to 10,000 lux can be used for 30 minutes in the morning to set the clock, especially in regions with limited natural light, and has shown effectiveness in treating seasonal and non-seasonal depression.

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How does light therapy compare to antidepressant medication for treating depression?

Studies have shown that light therapy (e.g., 10,000 lux for 30 minutes in the morning) can be more effective than placebo at two weeks and more effective than Prozac at eight weeks for both seasonal and non-seasonal depression.

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What is the difference in light intensity (lux) between outdoors and indoors?

Outdoors, light can be 10,000 lux shortly after dawn and up to 100,000 lux at noon. Indoors, near a window, it might be 1,000-3,000 lux, dropping to as little as 100 lux in the middle of a room, and around 90 lux in most domestic evening settings.

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Does getting bright light during the day protect against the negative effects of dim light at night?

Yes, recent studies indicate that exposure to 500 lux or more during the day for four to five hours can abolish even the subtle clock-shifting effects of dim light exposure in the evening.

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Does evening light always delay the clock and disrupt sleep?

While high intensity and long duration evening light can delay the clock, lower levels of light can have a direct alerting effect on the brain without necessarily shifting the clock, and this alerting effect, combined with stimulating content from screens, can still disrupt sleep.

1. Prioritize Morning Light Exposure

Expose yourself to light, ideally natural light outside, as close to your wake-up time as possible to advance your internal body clock and align it with the 24-hour day, which is crucial since most body clocks are slightly longer than 24 hours.

2. Use Light Box for Morning

If natural morning light is scarce (e.g., in winter or early mornings), use a light box set to 2,000-10,000 lux for 30 minutes during breakfast to help set your internal clock and combat seasonal or non-seasonal depression.

3. Maximize Daytime Light Exposure

Aim for 500 lux or more of light exposure for four to five hours during the day, as this cumulative exposure can mitigate and insulate you from the negative impacts of dim light in the evening.

4. Avoid Devices Before Bed

Ideally, avoid using devices for 30 minutes to an hour before bedtime to prevent their alerting effect on the brain and to reduce the synergistic alerting effects from activities like social media or emails.

5. Wind Down Before Sleep

Focus on relaxing and winding down before transitioning into sleep, as this process can make sleep easier by addressing underlying anxiety or sleep issues.

We as a society don't see light as a drug. We just think, well, we can expose ourselves to whatever light we want, whenever we want.

Russell Foster

Light was more effective than placebo at two weeks. Prozac was only statistically significant at eight weeks. And then light was more effective than Prozac.

Russell Foster

All life on Earth has evolved on a planet that rotates once every 24 hours. We're exposed to a light-dark cycle. The light-dark cycle has dominated our evolution and our biology.

Russell Foster

The more light exposure you get in the day, the more it insulates you from nighttime light exposure.

Dr. Chatterjee

Most people don't have a sleep problem. They have an anxiety or a sleep issue.

Russell Foster

Light Box Use for Circadian Rhythm Setting (Tromsø Method)

Russell Foster
  1. Use a light box set to produce more than 2,000 lux, potentially as high as 10,000 lux.
  2. Expose yourself to this artificial light for 30 minutes.
  3. Have breakfast in the room where the light box is being used.
  4. Utilize this daily to help set the internal clock to the external world, particularly in environments with limited natural light.

Winding Down Before Sleep

Russell Foster
  1. Ideally, avoid using electronic devices for 30 minutes to an hour before bedtime.
  2. Recognize that this helps reduce the direct alerting effect of light from screens on the brain.
  3. Minimize exposure to stimulating content like social media, emails, and active thinking associated with screens, as these can also have an alerting effect.
  4. Engage in activities that promote relaxation and help transition into sleep more easily.
50,000 cells
Number of cells in each suprachiasmatic nuclei (SCN) structure The master clock in the brain is a paired structure of about 50,000 cells.
90%
Percentage of people with a body clock longer than 24 hours This group needs a daily advance from morning light to entrain their clock.
2,000 to 10,000 lux
Light intensity for light boxes in Tromsø Used for 30 minutes during breakfast to set the clock in dark conditions.
2 weeks
Time for light therapy to show statistical significance for depression Light therapy (10,000 lux for 30 minutes in the morning) was more effective than placebo at this point.
8 weeks
Time for Prozac to show statistical significance for depression Prozac was only statistically significant at this point, making light therapy more effective earlier.
10,000 lux
Outdoor light intensity shortly after dawn on a clear day A benchmark for natural light exposure.
100,000 lux
Outdoor light intensity at noon on a clear day Can be reached even in Britain.
50,000-60,000 lux
Typical outdoor light intensity Most of the time.
1,000-3,000 lux
Indoor light intensity near a window on a sunny day When pointing a meter at the window.
100 lux
Indoor light intensity in the middle of a room Two to three meters from a window, a significant drop from outdoor levels.
90 lux
Typical evening light intensity in most domestic settings Relatively low light levels.
400-600 lux
Light intensity in a well-illuminated kitchen with LED lights Higher than typical domestic evening settings.
30 lux
Light intensity from a Kindle on maximum setting Very low light levels.
7.5 hours
Duration of dim light exposure to shift the clock Exposure to domestic light (e.g., 100 lux) for this duration can shift the clock, but can be abolished by bright daytime light.
4 hours
Duration of Kindle exposure in an experiment For five consecutive nights, using a Kindle at brightest intensity before bedtime.
10 minutes
Delay in sleep onset from Kindle exposure Statistically significant delay observed after 4 hours of Kindle use for five consecutive nights.
500 lux
Minimum daytime light intensity to abolish dim evening light effects Required for 4-5 hours during the day.
4-5 hours
Minimum duration of daytime light exposure to abolish dim evening light effects At 500 lux or more.
30 minutes to 1 hour
Recommended duration to avoid devices before bedtime To reduce alerting effects and aid winding down.