Michael Pollan: Could Psychedelics Solve the Mental Health Crisis? #69

Jul 3, 2019 Episode Page ↗
Overview

This episode features world-renowned author Michael Pollan discussing the renaissance of psychedelic research for mental health. He explores how therapist-guided psilocybin and LSD may treat conditions like depression, anxiety, and addiction by addressing root causes and fostering new perspectives.

At a Glance
9 Insights
1h 25m Duration
15 Topics
5 Concepts

Deep Dive Analysis

Current State of Mental Health Care

Introducing Michael Pollan's Work on Psychedelics

Historical Overview of Psychedelic Research

Psychedelics for Cancer-Related Anxiety and Depression

Mechanism: Addressing Mental Stuckness and Ego Dissolution

Importance of Set and Setting in Psychedelic Therapy

Case Study: Psilocybin for Fear of Cancer Recurrence

Psychedelics as a Catalyst for Perspective Shifts

The Need for New Mental Health Tools

Legality, Safety, and the 1960s Backlash

Psychedelics as a Tool for Social Change

Psychedelics as a Shortcut to Therapeutic Insights

Understanding Ego Dissolution and its Benefits

Microdosing: Definition and Research Status

The Future of Psychedelic Research and Mental Health

Psychedelics (Mind Manifesting)

Drugs like LSD and psilocybin were initially seen as wonder drugs for mental illness, with the term 'psychedelic' coined by an English psychiatrist in 1956/57, meaning 'mind manifesting.' They temporarily suppress the sense of self or ego, making beliefs more plastic and amenable to change, especially with therapeutic help.

Set and Setting

A concept introduced by Timothy Leary, emphasizing the importance of one's internal mindset and the external environment during a psychedelic experience. Therapists create an optimal mindset and environment, often with eye shades, to encourage an inward journey where the individual can confront what's troubling them.

Ego Dissolution

A notable effect of a high-dose psychedelic trip where the sense of self or ego dissolves or becomes permeable. This allows other thoughts to enter consciousness, new connections to be made, and provides a different perspective on one's identity, showing that one is not identical to the voice in their head.

Unitive Consciousness

A feeling experienced after ego dissolution during a psychedelic trip, where one feels part of something larger than themselves, merging with nature or the universe. This can lead to a profound sense of connection, empathy, and wellbeing.

Microdosing

The routine use of psychedelics in very small doses, typically a tenth of a normal dose, taken every few days (e.g., 10 micrograms of LSD every 3-4 days to avoid tolerance). Proponents claim it helps with wellbeing, depression, productivity, and creativity, but there is currently no robust scientific research to support these claims.

?
Why is Michael Pollan, a food writer, now writing about psychedelics?

Michael Pollan's core interest is humanity's engagement with the natural world. Just as food is a major way humans interact with nature, so are plants and fungi used to alter consciousness, which he sees as another branch of this interest, particularly in the context of health.

?
What mental health conditions can psychedelics potentially treat?

Psychedelics are being researched for conditions like alcoholism, depression, anxiety (especially in cancer patients), PTSD, obsessive-compulsive disorder, and potentially eating disorders, showing promising results in early trials.

?
How can psychedelics treat such a wide range of seemingly different conditions?

Many of these conditions are characterized by 'mental stuckness' or destructive thought loops and narratives. Psychedelics temporarily suppress the ego, making beliefs more plastic and amenable to change, thereby disturbing these deep grooves of thought.

?
What is the role of therapy in psychedelic treatment?

Psychedelic therapy is a package that includes significant psychotherapeutic support. Therapists help prepare the individual for the 'journey,' sit with them during the experience, and help interpret it afterward, creating an optimal mindset and environment.

?
Why were psychedelics made illegal and research banned in the 1960s?

Psychedelics became associated with the counterculture and were seen as disruptive by authorities like President Nixon, who believed they sapped the will to fight and fueled social upheaval. A moral panic, fueled by scare stories (some fabricated), led to their classification as illegal drugs with no medical use.

?
Are psychedelics addictive or toxic?

Classic psychedelics like psilocybin, LSD, and DMT are virtually non-toxic, with no established lethal dose, and are not considered addictive, contrary to their dangerous public image.

?
Can psychedelics help with social issues like tribalism and the environmental crisis?

Psychedelics induce a sense of unitive consciousness and connection to the natural world, increasing empathy and reducing tolerance for authoritarian ideas. While they address these issues at an individual level, how to apply this to cultural change is a complex question without a clear model.

?
Can the insights gained from psychedelics be achieved through other means like therapy or meditation?

Yes, psychedelics are seen as a shortcut to insights often achieved through extensive psychotherapy or thousands of hours of meditation, which also aim to create distance from the ego and cultivate new perspectives on consciousness.

?
What is microdosing and is it scientifically supported?

Microdosing involves taking very small, sub-perceptual doses of psychedelics routinely (e.g., every 3-4 days) to enhance wellbeing, creativity, or alleviate depression. While many users report benefits, there is currently no robust, placebo-controlled research to scientifically support these claims.

1. Psychedelic Therapy for Mental Illness

For individuals struggling with mental distress or illness (e.g., cancer-related anxiety/depression, alcoholism, depression, anxiety, OCD, eating disorders, addiction), structured psychedelic drug therapy under the guidance of therapists offers a potential paradigm shift. This approach aims to resolve symptoms and address fundamental root causes by temporarily suppressing the ego and making destructive beliefs more amenable to change.

2. Cultivate Ego Dissolution & New Perspectives

Engage in experiences (like high-dose psychedelic trips under supervision, or deep meditation) that can lead to ego dissolution, allowing one to realize they are not identical to their ego. This provides a “sample of a new way of thinking” and a healthy distance from the ego’s chatter, which can be reinforced through continued practice.

3. Question Ingrained Beliefs & Narratives

Actively challenge and question the beliefs and narratives about oneself and the world, especially those that are destructive or lead to “mental stuckness” and loops of rumination. This “perspectival shift” can lead to profound changes in behavior and outlook.

4. Adopt a Whole Food, Plant-Focused Diet

Prioritize eating real, whole foods and avoid ultra-processed, “edible food-like substances.” Consume “not too much” food, and structure your diet around “mostly plants,” making meat an occasional flavoring rather than a primary component, as this approach is strongly linked to health and well-being.

5. Implement Regular Meditation Practice

Incorporate meditation into your daily routine (e.g., using an app like Calm) to improve mood, enhance sleep quality, reduce feelings of anxiety, and boost productivity. This serves as a “mindfulness” component for overall health.

6. Reinforce Psychedelic Insights with Meditation

After having a psychedelic experience, use meditation as a practice to cultivate and reinforce the insights gained, strengthening new brain connections and maintaining the “sample of a new way of thinking” in daily life.

7. Consider Nutrient-Dense Supplements (If Needed)

If it’s not always possible to obtain all necessary nutrition from food, consider taking a nutrient-dense whole food supplement (containing vitamins, minerals, prebiotics, and digestive enzymes) each morning as an “insurance policy” to meet nutritional needs.

8. Explore Microdosing (With Caution)

Some individuals use microdosing (a tenth of a normal psychedelic dose, every 3-4 days) to potentially improve wellbeing, relieve depression, and enhance productivity or creativity. However, it’s crucial to note that there is currently no robust scientific research to support these claims, and effects may be largely due to the powerful placebo effect.

9. Research Psychedelics and Mental Health

For those interested in the therapeutic potential of psychedelics, especially for mental health conditions, follow ongoing research, consult reputable resources (e.g., michaelpollan.com), and seek out psychedelic societies for more information on trials and developments.

You're not administering a drug, a toxic drug every day. You're administering, in effect, an experience that this one administration of a drug gives you. And it is that experience that is not just relieving symptoms, but in many cases addressing fundamental causes. That's a really big deal.

Rangan Chatterjee

Eat food, not too much, mostly plants.

Michael Pollan

The word psychedelic, in fact, was coined by an English psychiatrist in 1956 or 57, and it means simply mind manifesting.

Michael Pollan

The more you heard about it, the more people had bad experiences.

Michael Pollan

I'm not identical to my ego. There is another ground on which to stand and confront life's challenges.

Michael Pollan

That was like 10 years of therapy rolled into one day.

Michael Pollan

We would not have Buddhism in America right now. And it's quite popular. And, and, and we would not have mindfulness, mindful meditation, if not for psychedelics.

Michael Pollan
80%
Success rate for cancer anxiety/depression in early studies Marked decreases in depression and anxiety scores among volunteers.
Two-thirds mark
Success rate for other indications (e.g., addiction) in pilot studies For conditions like smoking cessation and alcoholism.
Approximately 20%
Contribution of the food system to greenhouse gases Of total greenhouse gases.
2007 or 2008
Year Michael Pollan's 'Eat food, not too much, mostly plants' was written Over 10 years ago from the recording date.
30 years
Duration psychedelic research was banned From the 1960s until around 2000.
300 million
People struggling with depression worldwide Depression is the leading cause of disability worldwide.
Second
Ranking of suicide as a leading cause of death for people aged 15-25 Worldwide.
75,000 people
Deaths from opiate addiction in America (year before last) More than were killed in the entire Vietnam War.
10th of a normal dose
Typical microdosing dose E.g., 10 micrograms of LSD.
Once every three or four days
Typical microdosing frequency To avoid building up tolerance.