The New Science Of The Body Clock And How It Can Revolutionise Your Sleep and Health with Professor Russell Foster #292

Sep 6, 2022 Episode Page ↗
Overview

Professor Russell Foster, a circadian neuroscience expert from Oxford University, discusses how living out of sync with our body clocks impacts health, memory, and mental well-being. He shares practical strategies to optimize sleep and circadian rhythms, busting common myths and offering advice for various groups.

At a Glance
35 Insights
2h Duration
18 Topics
6 Concepts

Deep Dive Analysis

Undervalued Sleep and Its Cognitive Benefits

Sleep Deprivation's Impact on Worldview and Health

Morning Health Risks and Medication Timing

Importance of Morning Light for Circadian Alignment

Chronotypes: Genetic, Developmental, and Environmental Factors

Teenage Sleep Disruption and Light Exposure

Light's Interaction with the Body Clock and Device Myths

Optimizing Light Exposure for Better Sleep

Individual Sleep Needs and Debunking the Eight-Hour Myth

Consequences of Chronic Sleep Loss and Micro-sleeps

Dangers of Driving While Tired

Challenges and Mitigation for Shift Workers and New Parents

Sleep Disruption and Mental Health: A Causal Link

Sleep as a Therapeutic Target for Mental Health Conditions

Circadian Rhythms, Fertility, and Optimal Timing for Sex

Distinguishing Fatigue from Sleepiness and Stress Impact

Sleep Trackers: Utility, Limitations, and Anxiety

Normalizing Waking Up in the Middle of the Night

Sleep Consolidation

During sleep, the brain actively retains memories, engages in problem-solving for complex issues, and eliminates waste products like beta-amyloid, which is associated with dementia.

Circadian System/Body Clock

This internal biological system anticipates the demands of our daily rest-activity and sleep-wake cycles. It requires daily exposure to the light-dark cycle, particularly morning light, to align with the astronomical day.

Chronotype

An individual's innate preference for either morningness (lark) or eveningness (owl) is influenced by genetics, developmental stage (e.g., teenagers tend to be later types), and exposure to light.

Micro-sleeps

These are uncontrollable and unpredictable episodes of falling asleep, which pose extreme danger, especially when driving. Individuals often don't realize how tired they are before these episodes occur.

Glymphatic System

A recently discovered clearance system within the brain that becomes highly active during sleep. It is responsible for packaging up and disposing of toxic substances, including beta-amyloid, which is linked to dementia.

Fatigue vs. Sleepiness

Sleepiness is a state that is cured by sleep, whereas fatigue is a persistent, overwhelming chronic tiredness that does not resolve with extended sleep and often signals an underlying health issue.

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Why is sleep so important beyond just feeling rested?

Sleep consolidates memory, aids in problem-solving and innovation, and is crucial for the elimination of misfolded proteins like beta-amyloid, which is associated with dementia.

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Why is the period between 6 AM and 12 PM particularly dangerous for health?

This period involves a biological switch from rest to activity, causing blood pressure, glucose mobilization, and platelet stickiness to increase, predisposing vulnerable individuals to heart attacks and strokes.

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How does morning light impact our sleep-wake cycle?

Morning light is crucial for most people to 'advance' their internal body clock, helping to align it with the 24-hour day and making it easier to wake up and go to bed earlier.

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Can our chronotype (morning lark vs. night owl) be changed?

While genetics and age influence chronotype, it can be shifted, particularly in teenagers, through consistent light exposure; morning light advances the clock, while evening light delays it.

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Do blue-blocking glasses effectively improve sleep?

Blue-blocking glasses may help reduce alertness in the evening, making it easier to fall asleep, but their effect on significantly shifting the body clock is less clear and depends on light intensity and duration.

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Do we all need exactly eight hours of sleep per night?

No, individual sleep needs vary widely, typically between six and ten and a half hours; the key is to determine how much sleep allows for optimal daytime functioning without needing an alarm or craving caffeine.

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What are the long-term health consequences of chronic sleep loss?

Chronic sleep loss is linked to increased risk of obesity, type 2 diabetes, heart disease, higher rates of infection and cancer (e.g., in night shift workers), dementia, and mental health problems.

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How dangerous is driving while tired, especially in the early morning?

Driving at 4 AM can impair cognitive ability more severely than driving while legally drunk, significantly increasing the risk of dangerous micro-sleeps and severe crashes.

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How does sleep deprivation affect mental health?

There's a strong mechanistic overlap between neural circuits for sleep and mental health, meaning disrupted sleep can exacerbate mental health problems like paranoia and hallucinatory experiences, and vice versa.

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When is the best time for sex if a couple is trying to conceive?

Male fertility, including sperm motility, peaks in the morning due to rising testosterone, and sperm needs to be in the female reproductive tract two to three days before ovulation for the greatest chance of success.

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Is it normal to wake up in the middle of the night?

Yes, waking up in the middle of the night is a perfectly normal and common human and mammalian sleep pattern; staying relaxed and avoiding stimulating activities can help one fall back asleep.

1. Tune Lifestyle to Needs

Define your individual biological needs, social needs, and work requirements, then actively tune your lifestyle to align with them for optimal well-being.

2. Prioritize Sleep for Positive Outlook

Go to bed earlier and prioritize sleep, as a tired brain remembers negative experiences and forgets positive ones, influencing a negative world view.

3. Find Your Optimal Sleep Duration

Define how much sleep you need for optimal daytime performance, as individual sleep needs vary widely (6 to 10.5 hours), and avoid anxiety over not meeting a specific ’eight-hour’ myth.

4. Recognize Sleep Deprivation Signs

Monitor for signs of insufficient sleep, such as needing an alarm to wake, slow waking, caffeine cravings, increased irritability, or sleeping significantly longer on free days, to determine if you are getting enough rest.

5. Early Morning Natural Light

Aim for 10 to 30 minutes of natural, bright morning light as soon as possible after waking to advance your biological clock and shift your sleep-wake cycle earlier.

6. Morning Light for Circadian Alignment

Expose yourself to morning light, particularly for 90% of people whose body clocks naturally drift later, as morning light advances the clock, helping you get up and go to bed earlier.

7. Boost Daytime Light Exposure

Increase light in daytime spaces, especially for elderly individuals or those with mild dementia, and consider having breakfast by a window to improve sleep-wake behavior and potentially cognition by 10%.

8. Restrict Evening Light

To improve circadian rhythm and sleep, try to limit light exposure in the evening, even natural light, especially if you tend to go to bed too late.

9. Dim Lighting for Sleep Prep

Install low-lux, amber-colored bulbs in your bedroom and other evening spaces to reduce alertness and make it easier to fall asleep, as lower light intensity helps signal rest time.

10. Optimize Sleep Environment

Define your bedroom as a dedicated sleeping space by ensuring a comfortable mattress and pillows, and using distinctive scents like lavender to associate the space with sleep, embracing any sensory cues that help you relax.

11. Personalized Bedtime Routine

Implement a personalized winding-down routine before bed, such as reading under dim light or listening to relaxing music, to ease the transition from wakefulness to sleep.

12. Postpone Charged Discussions

Avoid emotionally charged discussions, such as family finances, before bed, as they can increase alertness and delay sleep onset; instead, carve out a different time for such conversations.

13. Wind Down to Reduce Stress

Recognize that poor sleep is often a stress problem, not just a sleep problem; implement a winding-down routine at the end of the day, leaving work at home and engaging in relaxing activities to reduce stress.

14. Banish Devices from Bedroom

To improve sleep, remove electronic devices like smartphones and tablets from your bedroom, as their presence and notifications can disrupt sleep and increase alertness.

15. Normalize Night Waking

Do not be alarmed if you wake up in the middle of the night, as biphasic or polyphasic sleep patterns are normal for mammals and do not necessarily mean the end of sleep.

16. Stay Calm During Night Waking

If you wake up during the night, stay calm, keep lights low, and avoid engaging in mentally stimulating activities like checking emails, as you will likely fall back to sleep naturally.

17. Conceal Illuminated Clocks

If you have an illuminated alarm clock, cover its display with tape to prevent clock-watching, which can cause anxiety about remaining sleep time and hinder falling back asleep.

18. Sleep Stabilization for Mental Health

Stabilize sleep-wake cycles, even partially, as it can reduce symptoms like paranoia and hallucinatory experiences, making sleep-wake systems a therapeutic target for mental health conditions.

19. Optimize Medication Timing

If prescribed anti-hypertensive or anti-stroke medication, take it before bedtime rather than in the morning, as this can halve the chances of stroke or heart attack over a 4-5 year period.

20. Early Eating for Metabolic Health

Concentrate your calorie intake during breakfast and lunchtime, aiming for a very light or earlier supper, as this is better for metabolic health and reduces the risk of weight gain, obesity, and type 2 diabetes.

21. Align Chronotype with Lifestyle

Understand your chronotype and actively manipulate it using light exposure (e.g., bright morning light, dim evening light) to align with your work or social demands, reducing vulnerability to sleep disruption.

22. Advance Late Chronotype with Light

If you are an extreme late chronotype struggling to wake early, set an alarm and get outside first thing in the morning or use a light box to advance your biological clock.

23. Light Box for Clock Setting

If natural morning light is difficult to access, use a light box providing 10,000 lux for 30 minutes to help set your biological clock and advance your sleep-wake cycle.

24. New Parents: Seek Support

New parents, especially mothers, should not feel guilty about being tired and should actively reach out for support from family or friends to mitigate chronic sleep loss, recognizing that humans did not evolve for sole parenting.

25. Shift Work Impact Education

Provide education for night shift workers and their families to understand the biological consequences of working at night, which can impact relationships (e.g., six times higher divorce rate in some sectors).

26. Match Shifts to Chronotype

Employers should chronotype their workforce to assign shifts that align with individuals’ natural morning or evening preferences, avoiding placing late chronotypes on early morning shifts.

27. Provide Driver Alertness Devices

Employers with night shift workers should make available or subsidize dashboard devices that measure head nod or car veering to alert tired drivers, mitigating the risk of accidents.

28. Post-Shift Sleep Facilities

Employers should consider providing facilities or arrangements for night shift workers to sleep after their shift, preventing them from driving home chronically tired and reducing accident risks.

29. Frequent Health Checks

Employers should institute higher-frequency health checks (e.g., every six months) for night shift workers to catch conditions like cancer, coronary heart disease, and type 2 diabetes before they become chronic.

30. Healthy Snacks for Night Shifts

Employers should provide easy-to-digest, high-protein snacks for night shift workers, as current offerings are often high in fat and sugar, contributing to health problems.

31. Sex for Sleep Promotion

Consensual sex or masturbation can promote sleep by relaxing individuals and releasing hormones that induce sleepiness.

32. Morning Sex for Fertility

For couples trying to conceive, consider having sex in the morning when male fertility peaks due to rising testosterone and optimal sperm motility.

33. Blue Blockers for Evening Alertness

If your goal is to reduce alertness in the evening, wearing blue light blocking glasses may be useful, as blue light is the most effective wavelength for increasing alertness.

34. Dynamic Bathroom Lighting

Consider using bathroom lighting that can switch from bright, alerting light in the morning to dimmer, less alerting light in the evening to support circadian rhythms and sleep preparation.

35. Basic Sleep Tracker Use

If using a sleep tracker, focus on basic metrics like sleep timing, duration, and fragmentation, and disregard advanced metrics like deep or REM sleep stages, as these are often inaccurate and can cause anxiety.

The tired brain remembers negative experiences, but forgets the positive ones.

Russell Foster

Alarm clocks stop the single most important behavioral experience we have.

Russell Foster

Chronic sleep loss is so much more than feeling tired at an inappropriate time. It's associated with an impact upon our health at every level.

Russell Foster

The clock always defers to the brighter light signal as being daytime.

Russell Foster

Asking a teenager to get up at 7 o'clock in the morning is like asking a 60-year-old to get up at 5 o'clock in the morning.

Russell Foster

If you are driving at four o'clock in the morning, your ability to process information is worse than if you were legally drunk.

Russell Foster
Almost 50% greater chance
Increased risk of stroke or heart attack Between 6 AM and 12 noon, due to biological shift from rest to activity.
50 to 100 times brighter
Natural light brightness compared to domestic light Shortly after dawn, natural light is significantly brighter than average indoor lighting conditions.
10,000 lux for 30 minutes
Light box intensity and duration to set the clock Can effectively advance the body clock, mimicking bright morning light.
10 minutes on average
Sleep delay from Kindle use After looking at a Kindle on its brightest intensity for four hours before bedtime for five consecutive nights (considered biologically meaningless).
6 hours to 10.5 hours
Natural human sleep span The typical range of sleep duration for humans, debunking the myth that everyone needs exactly 8 hours.
100,000 crashes
Estimated crashes in the US due to micro-sleeps On American freeways, possibly as high as 300,000 according to the American Automobile Association.
Worse (minus 20 on a scale where legally drunk is minus 15)
Cognitive impairment at 4 AM compared to being legally drunk Driving at 4 AM significantly impairs the ability to process information, making it more dangerous than driving while legally intoxicated.
97%
Night shift workers who do not adapt their body clock The vast majority of night shift workers fail to fully adapt their circadian rhythms to nocturnal work schedules.
6 times higher
Divorce rate for night shift workers In some sectors, compared to day shift workers, highlighting the social impact of shift work.
57%
Junior doctors experiencing crash or near-miss after night shift A study showed a high percentage of junior doctors had driving incidents after working night shifts.
10%
Cognition improvement in nursing homes with increased light Observed in individuals showing mild dementia by increasing light in day spaces and having breakfast by a window.
One night of no sleep
Increase in beta-amyloid deposition Shown to increase beta-amyloid deposition within the brain and its concentration in the cerebral spinal fluid.