How to Enhance Your Immune System | Dr. Roger Seheult

Episode 217 Feb 24, 2025 Episode Page ↗
Overview

Dr. Roger Seheult, a board-certified physician in internal medicine, pulmonary diseases, critical care, and sleep medicine, discusses preventing and treating infectious illnesses. He covers the benefits of light therapy (sunlight, infrared), hydrotherapy, NAC, and other science-based tools for improving immune and mitochondrial function.

At a Glance
19 Insights
3h 28m Duration
24 Topics
17 Concepts

Deep Dive Analysis

Pillars of Health for Avoiding Sickness (NEWSTART Mnemonic)

Sunlight's Deep Penetration and Mitochondrial Benefits

Benefits of Infrared Light in Green Spaces

Re-evaluating Sunlight Exposure and Cancer Risk

Sunlight's Impact on Influenza and COVID Incidence

Recommended Sunlight Exposure and Winter Challenges

Artificial Infrared Light and Metabolic Health

Historical Use of Sunlight in Healthcare and Modern Disconnect

Hospital Lighting, ICU Psychosis, and Patient Outcomes

Influenza, Flu Shots, and the Swiss Cheese Model of Protection

Hydration, Innate Immunity, and Hydrotherapy

Cold Hydrotherapy and Immune Cell Mobilization

N-Acetyl Cysteine (NAC) for Liver Support, Clotting, and Infection

NAC Dosage and Mucolytic Effects

Zinc Supplementation and Interferon Infusions

Eucalyptus Oil for Immune Stimulation and Congestion

Air Quality, Smoking, Vaping, and Nicotine Use

Benefits of Fresh Air and Forest Bathing

The 'Dark Days and Bright Nights' Problem

Long COVID, Mitochondrial Dysfunction, and Potential Treatments

COVID Severity, Smell Loss, and Olfactory Training

Mold Toxicity, Germ vs. Terrain Theory, and Immune Compromise

The Role of Trust, Spirituality, and Forgiveness in Health

Advocating for Better Hospital Care

NEWSTART Mnemonic

A mnemonic representing pillars of health: Nutrition, Exercise, Water, Sunlight, Temperance (avoiding toxins), Air, Rest, and Trust. These elements are considered fundamental for maintaining a healthy immune system and overall well-being.

Infrared Light Penetration

Long wavelength infrared light, a significant component of sunlight, can penetrate deeply into the human body (up to 8 cm) and through clothing. This deep penetration allows it to interact with internal biological processes, unlike visible or ultraviolet light.

Mitochondrial Melatonin Production

Mitochondria, the 'engines' of cells, produce melatonin on-site in concentrations 20 times higher than the pineal gland. This intracellular melatonin acts as an extremely powerful antioxidant, combating reactive oxygen species (free radicals) generated during energy production.

Mitochondrial Dysfunction

A fundamental issue underlying nearly every chronic disease, including diabetes, hypertension, heart disease, and dementia. It is also central to the mitochondrial theory of aging, where the efficiency of ATP (energy currency) production by mitochondria significantly declines after age 40.

Phytoncides

Airborne chemicals emitted by trees (e.g., Hinoki Cypress, fir, oak, pine) that can interact with the human immune system. Studies show these substances can stimulate the innate immune system, increasing natural killer cell activity and reducing stress hormones like cortisol.

ICU Psychosis

A condition where patients in intensive care units develop mental health disturbances, including psychosis, often due to disrupted circadian rhythms from constant artificial light and sleep deprivation. This condition typically resolves upon discharge from the hospital.

Swiss Cheese Model

A model illustrating how multiple layers of protection, each with its own flaws (like holes in Swiss cheese), can collectively prevent a problem. In health, it emphasizes that relying on a combination of interventions (e.g., nutrition, exercise, hygiene, vaccines) provides more robust protection against illness.

Innate Immune System

The body's first and non-specific line of defense, recognizing general pathological patterns (PAMPs) and damaged molecules (DAMPs) without prior exposure. It rapidly responds to threats, utilizing crucial molecules like interferon to combat infections.

Interferon

An extremely important molecule in the innate immune system with wide-ranging antiviral capabilities. It is effective against various viral strains and variants, and its suppression is a common strategy used by viruses to evade the immune response.

Hydrotherapy

The external application of water, particularly hot water, to transfer heat to the body, elevate core temperature, and stimulate the innate immune system. This process can significantly increase the secretion of interferon, a key antiviral molecule.

Demargination

A process triggered by cold exposure and subsequent vasoconstriction, where white blood cells (e.g., macrophages, neutrophils) that are normally attached to the inside of blood vessels are released into circulation. This effectively increases the number of circulating immune cells available to fight infection.

White Clots

Thrombi primarily formed by the polymerization of von Willebrand's factor and subsequent platelet aggregation, distinct from typical red blood cell clots. These were observed in high numbers in severe COVID-19 cases during autopsies, contributing to hypoxemia.

Dark Days and Bright Nights

A phenomenon describing the modern lifestyle characterized by insufficient natural light exposure during the day and excessive artificial light exposure at night. This imbalance negatively impacts circadian rhythms, metabolic health, and is associated with higher mortality.

Long COVID

A condition characterized by persistent symptoms such as fatigue, headaches, shortness of breath, or loss of taste/smell for more than 12 weeks after initial COVID-19 infection. It is often linked to underlying mitochondrial dysfunction and impaired fatty acid metabolism.

Olfactory Training

A protocol used to help recover the sense of smell after conditions like COVID-19, involving repeatedly smelling a variety of distinct odors (e.g., orange, lemon, coffee, chocolate). This stimulates and aids in the regeneration of olfactory neurons, which turn over in an activity-dependent way.

Germ Theory vs. Terrain Theory

Two perspectives on disease causation: Germ theory focuses on external pathogens (germs) as the primary cause, while terrain theory emphasizes the host's internal environment (immune system health). The episode highlights that both factors are crucial for understanding infection and illness, not one or the other.

Conditional vs. Unconditional Forgiveness

Conditional forgiveness requires an apology or remorse from the offending party, whereas unconditional forgiveness is granted regardless of the other person's actions. Studies suggest unconditional forgiveness is associated with less anxiety and fewer somatic complaints.

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How much daily sunlight exposure is recommended for health benefits beyond circadian rhythm?

Approximately 15-20 minutes of sunlight exposure per day is generally sufficient, as benefits diminish significantly after this point. This can be done at any time of day, though midday sun has higher UV, which can be mitigated by clothing.

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Can sunlight penetrate clothing?

Yes, infrared radiation from the sun, due to its long wavelength, can penetrate through clothes and skin, activating heat sensors and reaching much deeper into the body than visible light.

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Does the flu shot prevent infection?

No, the flu shot does not prevent infection, but it gives the immune system advanced notice of the antigen, which can significantly diminish the severity of symptoms if infection occurs, potentially preventing hospitalization.

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What are some known risks of the flu shot?

Risks include allergic reactions, such as anaphylactic shock. Historically, one particular strain in Europe was associated with a rash of narcolepsy, though this was an isolated incident and that brand was stopped.

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How does N-acetylcysteine (NAC) help with congestion?

NAC acts as a mucolytic by breaking the disulfide bonds that make mucus thick, thereby thinning it and making it easier to clear from the respiratory pathways. It's used to treat conditions like cystic fibrosis and can cause a runny nose.

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What is the most effective way to improve care when admitted to a hospital?

The most effective way is for the patient or a family member to communicate to the physician that they are familiar with the patient's condition and are prepared to ask intelligent, informed questions. This encourages the medical staff to be at their best and focus on effective answers.

1. Prioritize Daily Sunlight Exposure

Expose your skin to 15-20 minutes of natural sunlight daily, even on cloudy days, as infrared light penetrates deep into the body, stimulating mitochondria to produce melatonin and increase efficiency, which is crucial for overall health and combating age-related decline. If fair-skinned, wear a broad-rimmed hat and long-sleeved shirt to limit UV exposure while still benefiting from infrared light.

2. Ensure Dark Nights for Sleep

Maintain complete darkness in your sleeping environment, using blackout curtains or an eye mask, as even dim artificial light (e.g., 100 lux) at night can significantly suppress melatonin production and negatively impact morning blood glucose levels. If you need to navigate at night, use a flashlight pointed away from your eyes or a red light source.

3. Practice Mild-to-Moderate Exercise

Engage in mild to moderate exercise regularly, as this type of physical activity is shown to reduce inflammation in the body, contributing to a healthier immune system.

4. Adopt Natural, Unprocessed Nutrition

Focus on consuming foods that are as natural as possible and actively avoid processed foods to support overall health and immune function.

5. Prioritize 7-8 Hours of Sleep

Aim for 7-8 hours of quality sleep each night, as good sleep habits are directly linked to a much better immune system, improving antibody response and reducing the frequency of illness.

6. Cultivate Thankfulness & Forgiveness

Practice thankfulness and unconditional forgiveness, as these mental states are associated with less anxiety, fewer somatic complaints, and an overall greater sense of well-being, contributing to physical health.

7. Engage in Heat-Cold Contrast Therapy

Utilize hot baths, saunas, or hot fomentations (hot towels) to elevate your core body temperature to around 38-39°C (100.4-102.2°F), followed by a short cold exposure (e.g., a cold shower). Heat increases interferon secretion (a broad-spectrum antiviral), while cold causes vasoconstriction, liberating white blood cells into circulation and helping to ’lock in’ the heat.

8. Spend Time in Green Spaces

Seek out and spend time in natural green environments like forests or parks, as trees release phytoncides that stimulate the innate immune system and reduce stress, and green leaves reflect additional beneficial infrared light.

9. Maintain Adequate Hydration

Drink sufficient water to maintain proper sodium concentration in your body, as adequate hydration is essential for kidney function, toxin removal, and overall cellular health.

10. Avoid Toxins (Smoking, Vaping)

Refrain from inhaling anything other than clean air or prescribed medicines, specifically avoiding smoking and vaping, as these introduce irritants and toxins that are detrimental to lung health and overall well-being.

11. Consider NAC for Flu/Cold Symptoms

Take 600 milligrams of N-acetylcysteine (NAC) twice a day during winter or flu season for up to three months to replenish glutathione, act as a mucolytic, and significantly reduce the severity of influenza symptoms like runny nose and sore throat.

12. Consider Zinc Supplementation

Supplement with up to 40 milligrams of elemental zinc daily, as zinc acts as a cofactor for several immune system enzymes, potentially benefiting overall immune function. Monitor copper levels with long-term high-dose zinc use.

13. Use Eucalyptus Oil Externally for Congestion

If congested, use eucalyptus oil externally by rubbing a few drops on the skin or adding it to hot water for steam inhalation. Do not ingest eucalyptus oil internally, as it can be toxic.

14. Do Not Suppress Fever (Unless Advised)

Generally, avoid immediately suppressing a fever with medication, as fever is a natural immune response that helps the body fight infection by increasing the production of antiviral interferon.

15. Utilize Intermittent Fasting for Mitochondrial Health

For conditions like long COVID or general metabolic health, consider practicing intermittent fasting (e.g., avoiding food after 5:30 PM) to allow the body to generate new, healthy mitochondria by breaking down damaged cells and promoting regeneration.

16. Use Artificial Red/Near-Infrared Light

If natural sunlight exposure is consistently scarce (e.g., in winter in northern latitudes), consider supplementing with low-amplitude red/near-infrared lamps for 15-20 minutes a day to support mitochondrial function. Avoid excessive intensity, as more is not necessarily better.

17. Humidify Air in Cold/Dry Environments

If prone to respiratory issues in cold, dry environments, consider using a humidifier, especially at night, to prevent drying out of respiratory pathways.

18. Practice Smell Training

If experiencing a loss of smell or taste (e.g., post-COVID), engage in smell training using a variety of distinct odors (e.g., lemon, coffee, chocolate) to help reactivate and regenerate olfactory neurons.

19. Communicate Knowledgeably in Hospital

When a loved one is admitted to the hospital, ask intelligent, informed questions about their disease and treatment plan. This signals to the medical staff that you are engaged and knowledgeable, which can lead to more thorough and attentive care.

Sunlight strongly protects against getting influenza.

Dr. Roger Seheult (quoting Harvard Kennedy School Study)

Sunlight, Time for a Rethink.

Dr. Roger Seheult (quoting Richard Weller in Journal of Investigative Dermatology)

When it comes to treating the whole patient, the one thing that more than anything else is beneficial for these soldiers to recover is fresh air. But, she said, a very close second is direct sunlight, getting them out into sunshine, getting them out into direct sunlight.

Dr. Roger Seheult (quoting Florence Nightingale)

This idea of keeping the lights on after 9 o'clock, it's a wretched, health-destroying habit. Every light should be extinguished, she said, after 9 o'clock.

Dr. Roger Seheult (quoting Ellen G. White)

Eucalyptus oil is never recommended to be taken internally. There's actually been reported deaths from taking too much eucalyptus oil.

Dr. Roger Seheult

Hydrotherapy for Illness

Dr. Roger Seheult
  1. Apply hot towels (fomentations) or take a hot bath/sauna for about 20 minutes until sweating begins, to elevate core body temperature.
  2. Follow with a very short (approximately 1 minute) cold exposure, such as a cold shower or rubbing the chest with cold water, to cause vasoconstriction and demargination of white blood cells.

Long COVID Mitochondrial Regeneration

Dr. Roger Seheult
  1. Practice intermittent fasting, avoiding food after a certain time (e.g., 5:30 PM) to allow the body to break down damaged cells and regenerate new ones.
  2. Increase daily sunlight exposure to support mitochondrial function and potentially mitigate inflammation.

Olfactory Training for Smell Loss

Dr. Roger Seheult
  1. Repeatedly smell a variety of distinct odors (e.g., orange, lemon, coffee, chocolate).
  2. Continue this training to stimulate and help regenerate olfactory neurons and their connections in the brain.
52%
Percentage of sun's energy in infrared spectrum Remaining 38% is in the visible spectrum.
20 times higher
Melatonin concentration in mitochondria vs. pineal gland Mitochondrial melatonin is used on-site as an antioxidant, not for circadian rhythm.
70%
Drop in mitochondrial ATP output after age 40 This decline significantly impacts cellular function and is linked to the mitochondrial theory of aging.
13%
Reduction in HSCRP levels after planting trees in Louisville, KY HSCRP is a surrogate marker for inflammation; this reduction is comparable to exercising three times a week.
93%
Time spent indoors by Americans 86% inside buildings and 6-7% inside vehicles.
50%
Reduction in hospitalizations for COVID-19 with 940nm infrared light therapy Achieved with 15 minutes/day for 7 days in a randomized, placebo-controlled, double-blinded study.
12 days
Average length of hospital stay for COVID-19 in control group Reduced to 8 days in the intervention group using infrared light therapy.
130 milliwatts per square centimeter
Solar radiation reaching Earth's atmosphere Approximately 100 milliwatts per square centimeter reaches the Earth's surface.
20 milliwatts per square centimeter
Infrared light from the sun reaching Earth's surface This is significantly higher than the 2.9 milliwatts used in a therapeutic study.
20-30%
Predicted percentage improvement in obesity/metabolic disease metrics from 15 minutes/day sunlight exposure This is independent of caloric intake or additional exercise.
15 seconds
Artificial light exposure duration to significantly quash melatonin at night Due to the increased sensitivity of the eye's rod system and specialized cells at night.
100-400 lux
Lux level of a typical hotel room wall panel light Despite appearing dim, this level of light can significantly impact glucose regulation and circadian rhythm.
39 degrees Celsius (102.2 Fahrenheit)
Core body temperature for a tenfold increase in interferon secretion (in vitro) Observed in lymphocytes bathed in LPS.
38 degrees Celsius (100.4 Fahrenheit)
Core body temperature for a dramatic increase in STAT/JAK signaling (in vivo) This increase in temperature upregulates transcription in the nucleus, leading to more interferon.
600 milligrams
NAC dosage for flu symptom reduction Taken twice a day during the winter season (3-6 months) in a multi-centered, double-blinded, placebo-controlled trial.
50%
Absolute risk reduction in flu symptoms with NAC supplementation This translates to a number needed to treat of 2, indicating high efficacy in reducing symptom severity.
40 milligrams
Recommended daily elemental zinc intake High zinc intake should be monitored for potential copper deficiency.