How to Focus to Change Your Brain

Episode 6 Feb 8, 2021 Episode Page ↗
Overview

Andrew Huberman, a Stanford neurobiology professor, explains neuroplasticity, distinguishing childhood from adult brain change. He details the neurochemicals (epinephrine, acetylcholine) crucial for learning and provides tools like visual focus, sleep, and NSDR to enhance adult brain plasticity.

At a Glance
22 Insights
1h 27m Duration
18 Topics
8 Concepts

Deep Dive Analysis

Introduction to Neuroplasticity and its Importance

Developmental vs. Adult Neuroplasticity: Brain Changes Over Time

Brain Customization and Hard-Wired Circuits

The Myth of New Neuron Addition in the Adult Brain

Brain Reorganization Through Sensory Impairments

The Kennard Principle: Brain Injury and Recovery

Awareness as the First Step for Brain Change

Neurochemicals that Drive Brain Plasticity

The Role of Epinephrine (Adrenaline) in Alertness

Acetylcholine: The Brain's Spotlight for Focus

The Chemical Trio for Massive Brain Change

Behavioral Tools for Enhancing Focus

Visual Focus as a Gateway to Mental Focus

Blinking and Sustained Visual Attention

ADHD and Attention in the Modern World

Optimal Learning Bouts and Ultradian Cycles

The Role of Sleep and Non-Sleep Deep Rest in Plasticity

Synthesis and Future Topics on Neuroplasticity

Neuroplasticity

The brain and nervous system's inherent ability to change itself in response to experience. This process allows individuals to learn new things, forget painful experiences, and adapt to various life circumstances by acquiring new capabilities.

Developmental Plasticity

The form of neuroplasticity that occurs from birth until approximately age 25. It primarily involves the refinement of neural connections through the removal of connections that are not well-used and the strengthening of those that are, often through passive experience.

Critical Period

A specific time window early in development when the nervous system is highly sensitive to certain environmental inputs. If these inputs are absent or altered during this period, the brain may wire itself differently, making it harder to correct later in life.

Epinephrine (Adrenaline)

A neurochemical released from the locus coeruleus in the brain, primarily during states of high alertness. Its function is to increase the overall activity and excitability of neurons, making the brain more receptive to potential changes.

Acetylcholine

A neuromodulator released from two key brain regions (brainstem and nucleus basalis) that acts like a 'spotlight' for attention. It amplifies specific sensory inputs or mental focus, making them more salient and crucial for enabling neuroplastic changes when combined with epinephrine.

Mental Focus Follows Visual Focus

A principle stating that the ability to concentrate mentally is closely linked to one's ability to visually focus. By practicing sustained visual attention on a small target, individuals can enhance their broader cognitive or mental focus capabilities, as it activates shared neural mechanisms.

Ultradian Cycles

Natural biological rhythms that typically last about 90 minutes. These cycles suggest that optimal learning bouts for adults should be approximately 90 minutes, allowing for periods of intense focus followed by rest or mind-wandering.

Non-Sleep Deep Rest (NSDR)

Protocols such as yoga nidra or brief naps (under 90 minutes) that involve lying very still while maintaining an active mind. NSDR can significantly restore cognitive and physical energy and has been shown to accelerate learning when performed immediately after a focused learning session.

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What is neuroplasticity and why is it important?

Neuroplasticity is the brain and nervous system's ability to change in response to experience, allowing individuals to learn new things, forget painful experiences, and adapt to life's challenges by becoming better.

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How does neuroplasticity differ between childhood and adulthood?

From birth until about age 25, developmental plasticity primarily involves removing unneeded connections and strengthening others through broad experience. After age 25, adult neuroplasticity requires deliberate engagement and specific internal states for changes to occur and persist.

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Can adults grow new neurons?

After puberty, the human brain adds very few, if any, new neurons. While some evidence suggests new neurons can be added to the olfactory bulb and a very small number to the hippocampus, it's not a significant source of brain change in adulthood.

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What is the Kennard Principle?

The Kennard principle states that if one is to sustain a brain injury, it is better to have it early in life, as the young brain has a greater capacity for recovery and reorganization compared to the adult brain.

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What neurochemicals are essential for adult neuroplasticity?

Epinephrine (for alertness) and acetylcholine (for spotlighting attention from two specific brain sources) are the key neurochemicals that, when released together, create the conditions for rapid and massive brain change.

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How can I increase my focus without drugs?

One effective behavioral method is to practice visual focus by maintaining a steady gaze on a small target, as mental focus is anchored to visual focus and this activates the necessary neurochemical systems for attention.

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When does actual brain change (plasticity) occur?

Real neural plasticity, involving the strengthening or weakening of connections, primarily occurs during sleep, especially deep sleep, after periods of focused learning during wakefulness.

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How long should a learning session be for optimal plasticity?

Optimal learning bouts for adults typically align with ultradian cycles, lasting about 90 minutes, allowing for an initial warmup, about an hour of sustained focus, and then a period of rest or mind-wandering.

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Can non-sleep deep rest (NSDR) help with learning?

Yes, engaging in NSDR protocols or brief naps (under 90 minutes) immediately after a focused learning session can significantly accelerate the rate of learning and plasticity by aiding in the consolidation of information.

1. Enable Adult Neuroplasticity

To achieve neuroplasticity as an adult, you must deliberately engage alertness (epinephrine release) and focused attention (acetylcholine release) to signal the brain that change is necessary.

2. Prioritize Sleep for Learning

Master your sleep schedule and ensure sufficient sleep to achieve the necessary alertness for deliberate, focused learning, as your ability to focus is directly proportional to your sleep quality.

3. Reinforce Learning During Sleep

Understand that actual neural plasticity and the strengthening of learned circuits occur during sleep, making quality sleep essential after focused learning to acquire knowledge permanently.

4. Accelerate Learning with NSDR

Immediately after a focused learning bout, engage in a 20-minute non-sleep deep rest (NSDR) protocol or a shallow nap (90 minutes or less) to significantly accelerate the rate of learning and plasticity for that information.

5. Structure Learning Bouts

Organize learning sessions into approximately 90-minute ultradian cycles, allowing for a 5-10 minute warm-up and aiming for about an hour of sustained, deep focus within the session.

6. Practice Visual Focus

Improve mental and cognitive focus by regularly practicing visual focus, such as staring intently at a small target for 60-120 seconds at the distance of your intended work.

7. Eliminate Learning Distractions

During focused learning bouts, eliminate all distractions by turning off Wi-Fi and placing your phone or other tempting devices out of reach to maintain concentration.

8. Re-anchor Drifting Attention

When your attention inevitably drifts during a learning task, consciously and repeatedly re-anchor it, using visual focus (if sighted) to guide it back to the material.

9. Post-Learning Wordlessness

After an intense focused learning bout, engage in motor activity involving self-generated optic flow (e.g., walking, running, cycling) without complex thought, allowing your mind to drift as a form of non-sleep deep rest to accelerate learning.

10. Cultivate Diverse Motivation

Identify multiple reasons (e.g., excitement for a goal, fear of not following through) to motivate yourself, ensuring sufficient alertness, energy, and attention for learning and brain change.

11. Identify Peak Alertness Times

Determine your natural peak periods of alertness during the day and dedicate these times to focused learning activities that align with your goals, as this provides a natural advantage for learning.

12. Protect Peak Alertness

Safeguard your peak alertness periods from passive observance or activities that are meaningless or not aligned with your goals, as this time is a valuable asset for effective learning.

13. Enhance Auditory Focus

To improve auditory focus, especially when listening intently, close your eyes to create a ‘cone of auditory attention’ and minimize visual distractions.

14. Limit Motion Stimuli

Reduce your exposure to excessive visual motion stimuli, such as dramatic videos, to prevent diminishing your ability to focus on less dynamic content like text or auditory information.

15. Form Habits with Repetition

For behavioral changes related to habit formation, focus on a strategy of ‘repetition, reward, repeat’ rather than intense focus or high emotionality.

16. Identify Change Goal

Recognize and clearly identify what specific behavior, mindset, or skill you want to change or learn in your nervous system, as this awareness is the first step in neuroplasticity.

17. Supplement Vitamin D3 K2

Supplement with Vitamin D3 K2, as D3 is essential for brain/body health (many are deficient even with sun) and K2 regulates cardiovascular function and calcium.

18. Use Meditation/NSDR App

Utilize a meditation app like Waking Up, which offers meditation programs, mindfulness training, yoga nidra, and NSDR protocols, to restore cognitive and physical energy, even with short 10-minute sessions.

19. Exercise Caffeine Caution

Use caffeine in reasonable amounts to increase alertness (epinephrine), ensuring it doesn’t interfere with your sleep, as it can be a relatively safe way to boost focus.

20. Exercise Nicotine Caution

(Cautionary) Be extremely careful if considering cholinergic agents like nicotine, alpha-GPC, or choline to increase focus, as their use should be limited to create distinct windows of attention for plasticity, not constant reliance.

21. Beware Dopamine Over-Reward

Be wary of receiving too much dopamine from external validation for intending to achieve a goal, as this can diminish the internal drive to pursue the actual accomplishment.

22. Avoid Constant Max Focus

Do not attempt to maintain maximum focus all day long; instead, structure your learning into specific 90-minute bouts to optimize brain function and prevent burnout.

All of us were born with a nervous system that isn't just capable of change, but was designed to change.

Andrew Huberman

Developmental plasticity, the neuroplasticity that occurs from the time we're born until about age 25 is mainly a process of removing connections that don't serve our goals well.

Andrew Huberman

The nervous system doesn't just change because you experience something unless you're a very young child.

Andrew Huberman

The experiences that you pay super careful attention to are what open up plasticity.

Andrew Huberman

If you get these three things, if you can access these three things of epinephrine acetylcholine from these two sources, not only will the nervous system change, it has to change, it absolutely will change.

Andrew Huberman

Your brain does not distinguish between doing things out of love or hate, anger or fear. It really doesn't. All of those promote autonomic arousal and the release of epinephrine.

Andrew Huberman

The best way to get better at focusing is to use the mechanisms of focus that you were born with.

Andrew Huberman

Neural plasticity doesn't occur during wakefulness. It occurs during sleep.

Andrew Huberman

Adult Neuroplasticity Protocol (High Focus Regime)

Andrew Huberman
  1. Achieve a state of alertness through sufficient sleep, hydration, and mental motivation (e.g., drawing on love, fear, or a combination of reasons to accomplish a goal).
  2. Engage in focused attention on the specific material or skill to be learned. For most people, this means practicing visual focus by maintaining a steady gaze on a small target (e.g., text on a screen or paper). If learning auditory information, closing eyes can enhance focus.
  3. Maintain this focused effort for approximately 90-minute bouts, understanding that the beginning and end may involve some flickering of attention, but aiming for sustained focus in the middle hour.
  4. Immediately after the focused learning bout, engage in non-sleep deep rest (NSDR) for about 20 minutes, or a period of deliberate disengagement such as walking, running (self-generated optic flow), or simply sitting mindlessly, allowing thoughts to drift.
  5. Ensure adequate deep sleep during the subsequent night(s) to allow the neural circuits highlighted during wakefulness to strengthen and consolidate the learning.
25 years old
Age when everything changes for brain plasticity Plus or minus a year or two; after this age, deliberate processes are needed for brain changes to occur and stick.
90 minutes
Duration of a focused learning bout This aligns with ultradian cycles and should include a 5-10 minute warmup, aiming for about an hour of sustained focus.
20 minutes
Duration of NSDR or shallow nap for accelerated learning When performed immediately after a learning task, it can significantly increase learning rates.
About 5
Number of Nicorette pieces chewed per hour by a Nobel laureate Used to increase alertness and focus; not a recommendation for general use.